Faculty or Staff Name:

LaneHead.jpgR. Lane Coffee, Jr., PhD, MS
Visiting Assistant Research Professor of Emergency Medicine
Program Manager, Indiana CTSI
Office Location & Contact
Health Information & Translational Sciences (HITS) Bldg. - Suite 1000
410 W. 10th Street, Indianapolis, IN 46202


Phone: (317) 278-2150


Northwestern University
Post-Doctoral Research Fellowship, Neurobiology, 2013

Fred Hutchinson Cancer Research Center
Post-Doctoral Research Fellowship, Vaccine & Infectious Disease, 2012

Vanderbilt University
PhD, Class of 2011

Clemson University
MS, Class of 2002

Berry College
BS, Class of 1999

About me

Dr. Coffee has joined the Department of Emergency Medicine as a Visiting Assistant Research Professor as well as a Project Manager of the Project Development Team (PDT) Program at the Indiana Clinical and Translational Sciences Institute (CTSI).

In the Department of Emergency Medicine, Dr. Coffee serves as a resource for trainee- and faculty-related research endeavors including project/study development as well as protocol and grant development and writing. Within the CTSI, he is responsible for managing research portfolios of investigators utilizing the PDT program as well as direct oversight and management of the Multi-PI Program Project Planning PDT (P4-PDT), a mechanism that supports the development of large multi-investigator and/or multi-project, milestone-driven, bench to bedside studies with annual direct budgets of $500K and higher. He is also working with colleagues within the CTSI and School of Medicine to develop and implement a new grant writing resource (e.g. one-on-one meetings, workshops, courses) that will be available to investigators for assistance with all aspects of grantsmanship.

Before coming to IU, Dr. Coffee was in research and grants administration at the University of South Dakota. He received a Ph.D. in neuroscience from Vanderbilt University, a M.S. in chemistry from Clemson University, and completed post-doctoral training at Northwestern University and at the Fred Hutchinson Cancer Research Center.

When he isn’t working, Dr. Coffee enjoys running, traveling to sunny destinations, and exploring local restaurants.


Recent Publications

In vivo neuronal function of the fragile X mental retardation protein is regulated by phosphorylation.
Fragile X mental retardation protein has a unique, evolutionarily conserved neuronal function not shared with FXR1P or FXR2P.
Positive regulation of Raf1-MEK1/2-ERK1/2 signaling by protein serine/threonine phosphatase 2A holoenzymes.
From triplex to B-form duplex stabilization: reversal of target selectivity by aminoglycoside dimers.
Particle beam glow discharge mass spectrometry: spectral characteristics of nucleobases.
Neomycin binding to Watson-Hoogsteen (W-H) DNA triplex groove: a model.
Neomycin-induced hybrid triplex formation.
Aminoglycoside-nucleic acid interactions: remarkable stabilization of DNA and RNA triple helices by neomycin.
DNA triple helix stabilization by aminoglycoside antibiotics.
Identification of kinase-phosphatase signaling modules composed of p70 S6 kinase-protein phosphatase 2A (PP2A) and p21-activated kinase-PP2A.


1701 N. Senate Blvd, B401 | Indianapolis, IN 46202 | (317) 962-5975