Faculty or Staff Name:

Mitchell_Alice.jpgAlice Mitchell, MD
Assistant Professor of Emergency Medicine

Office Location & Contact
Faculty Office Building, Eskenazi Health
640 Eskenazi Ave, Indianapolis, IN 46202

Phone: (317) 880-3900


Carolinas Medical Center
Fellowship, Research, 2006
Residency, Emergency Medicine, 2002

University of North Carolina
Certificate of Public Health, 2006

University of Utah
MD, Class of 2006
MS, Chemistry, Class of 1997
BS, Chemistry, Class of 1995

Curriculum Vitae

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About me

Alice and her family are recent arrivals to Indianapolis, where they very much enjoy biking on the Monon Trail, visiting the museums downtown and eating at lots of great restaurants.

Current Research

I have broad interest in diagnostic decision-making and the use of diagnostic imaging.  My research focus is acute kidney injury, specifically contrast-induced nephropathy.  I am interested in understanding how this type of kidney injury affects the short and long-term health of patients, in improving the identification patients at risk and preventing contrast-induced nephropathy.  As an emergency physician, I understand the importance of advancements in diagnostic testing, especially CT imaging. I also recognize the unique challenges of integrating research advancements in the clinical setting.  In my research, I take an integrative approach that involves a unique collaboration with nephrologists, radiologists, biostatisticians and operational engineers to evaluate how new biological markers and clinical decision rules will perform in the clinical setting.



  1. Crouch BI, Caravati EM, Mitchell A, Martin A. Poisoning in older adults: a 5-year experience of U.S. poison control centers. (2004) The Annals of Pharmacotherapy.38:2005-2011. PMID: 15522976
  2. *Kline JA, Mitchell AM, Kabrhel C, Richman PB, Courtney MD. Clinical criteria to prevent unnecessary diagnostic testing in emergency department patients with suspected pulmonary embolism. Journal of Thrombosis & Haemostasis. 2004;2:1247-55. PMID: 15522976
  3. *Kline JA, Mitchell AM, Runyon MS, Jones AE, Webb WB. Electronic medical record review as a surrogate to telephone follow-up to establish outcome for diagnostic research studies in the emergency department. Academic Emergency Medicine. 2005;12:1127-33. PMID: 16166598.
  4. *Mitchell AM, Brown MD, Menown IBA, Kline JA. Novel protein markers of acute coronary syndrome complications in low-risk outpatients: a systematic review of potential use in the emergency department. Clinical Chemistry.2005; 51:2005-2012. PMID: 16166170.
  5. *Mitchell AM, Garvey JL, Chandra A, Diercks D, Pollack CV, Kline JA. Prospective multicenter study of quantitative pretest probability to exclude acute coronary syndrome for patients evaluated in emergency department chest pain units. Annals of Emergency Medicine. 2006;47:438-447. PMID: 16631984.
  6. *Kruse L, Mitchell AM, Camargo CA, Hernandez J, Kline JA. Frequency of thrombophilia-related genetic variations in patients with idiopathic pulmonary embolism in an urban emergency department. Clinical Chemistry. 2006;52:1026-1032. PMID: 16574759.
  7. *Mitchell AM, Garvey JL, Kline JA. Multimarker Panel to rule out acute coronary syndromes in low-risk patients. Academic Emergency Medicine. 2006;13(7):803-806. PMID: 16723729.
  8. *Kline JA, Runyon MS, Webb WB, Jones AE, Mitchell AM. Prospective study of the diagnostic accuracy of the simplify D-dimer assay for pulmonary embolism in emergency department patients. Chest. 2006;129(6):1417-23. PMID:16778257
  9. *Mitchell AM, Kline JA. Contrast Nephropathy Following Computed Tomography Angiography of the Chest for Pulmonary Embolism in the Emergency Department. Journal of Thrombosis & Haemostasis. 2007;5(1):50-54. PMID: 17026644.
  10. *Kline JA, Courtney DM, Kabrhel C, Moore CL, Smithline HA, Plewa MC, Richman PB, O’Neil BJ, Nordenholz KE, McCubbin TR, Beam DM, Than M, Mitchell AM, Johnson CL, Camargo CA. Prospective, Multicenter Validation of Pulmonary Embolism Rule-Out Criteria. Journal of Thrombosis and Haemostasis. 2008;6:772-780. PMID: 20015156
  11. *Mitchell AM, Kline JA. Systematic Bias Introduced by the Informed Consent Process In a Diagnostic Study. Academic Emergency Medicine.2008;15:225-230. PMID: 18304052.
  12. *Kline JA, O’Malley PM, Tayal VS, Snead G, Mitchell AM,. Emergency Clinician-Performed Compression Ultrasonography to Diagnose and Exclude Deep Vein Thrombosis of the Lower Extremity. Annals of Emergency Medicine. 2008;57:437-445. PMID: 18562044.
  13. *Nordenholz KE, Mitchell AM, Kline JA. Direct comparison of the diagnostic accuracy of 50 protein biological markers of pulmonary embolism for use in the emergency department. Academic Emergency Medicine. 2008;15(9):795-799. PMID: 19244629.
  14. *Mitchell AM, Nordenholz KE, Kline JA. Tandem measurement of D-dimer and Myeoloperoxidase or C-reactive protein to effectively screen for pulmonary embolism in the emergency department. Academic Emergency Medicine. 2008;15(9):800-805. PMID: 18821859.
  15. *Mitchell AM, Jones AE, Tumlin JA, Kline JA. The incidence of Contrast-Induced Nephropathy following Contrast-Enhanced Computed Tomography in the Outpatient Setting. Clinical Journal of the American Society of Nephrology. 2010; 5:4-9. PMID: 19965528; PMCID: 2801649.
  16. *Mitchell AM, Jones AE, Tumlin JA, Kline JA. Immediate Complications of Intravenous Contrast for Computed Tomography Imaging in the Outpatient Setting are Rare. Academic Emergency Medicine. 2011;18:1005-9. PMID 21854485.
  17. *Mitchell AM, Jones AE, Tumlin JA, Kline JA. Prospective Study of the Incidence of Contrast-Induced Nephropathy among Patients Evaluated for Pulmonary Embolism by Contrast-Enhanced Computed Tomography. Academic Emergency Medicine. 2012;19:618-25. PMID 22687176.
  18. *Traub SJ, Mitchell AM, Jones AE, Tang A, O'Connor J, Nelson T, Kellum J, Shapiro NI. N-Acetylcysteine Plus Intravenous Fluids Versus Intravenous Fluids Alone to Prevent Contrast-Induced Nephropathy in Emergency Computed Tomography. Annals of Emergency Medicine. 2013; In press.
  19. *Mitchell AM, Jones AE, Tumlin JA, Kline JA. 1-year mortality following contrast-induced nephropathy. American Journal of Internal Medicine. 2013;1:1-6.
  20. *†Cabey WV, MacNeill E, White LN, Norton J, Mitchell AM. Frequent Pediatric Emergency Department Use in Infancy and Early Childhood. Pediatric Emergency Care. 2013;In press.

1701 N. Senate Blvd, B401 | Indianapolis, IN 46202 | (317) 962-5975